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राष्ट्रीय पशु जैव प्रौद्योगिकी संस्थान
National Institute of Animal Biotechnology
An Autonomous Institute of the Department of Biotechnology,
Ministry of Science and Technology, Government of India
राष्ट्रीय पशु जैव प्रौद्योगिकी संस्थान
National Institute of Animal Biotechnology
An Autonomous Institute of the Department of Biotechnology,
Ministry of Science and Technology, Government of India
Education:
Sarwar Azam completed M Tech degree in Computational and Systems Biology from Jawaharlal Nehru University in 2009. After working for a short period at National Institute of Plant Genome Research (NIPGR), he joined International Crop Research Center for the Semi-Arid Tropic (ICRISAT) in 2010 as Visiting Scientist (Bioinformatics). Later he continued as a Special Project Scientist at ICRISAT in the field of computational genomics. He joined NIAB in November 2013.
Selected awards, honors and fellowships:
1. Certificate of Appreciation for the outstanding contribution in the area of Functional Genomics and Bioinformatics as part of Bioclues Innovation, Research and Development (BIRD) award, 2011
2. Exceptional Scientific Article in a High Impact Journal Award, ICRISAT, 2011
3. CSIR – UGC NET examination in Life sciences held in June 2008, December 2008 & June 2009
4. DBT fellowship 2007-2009 for M.Tech. course
5. BCIL Fellowship for BITP from DBT, Govt. of India, 2006
Sarwar’s research experience spans genetics, genomics and computational biology. His major contribution has been in the field of genome sequencing where he generated reference sequences for animal and plant genomes i.e., Bos Indicus (Cattle), Cicer arietinum (chickpea) and Cajanus cajan (pigeonpea) and bacterial genomes i.e., Sphingopyxis wildii and Sphingobium fuliginis. He has also contributed in finding quantitative trait loci (QTLs) for different traits in chickpea and identified candidate genes for various traits by analysing RNAseq data in different species. He also developed pipeline to analyse NGS data for SNPs identification (ISMU), synteny visualisation (GCT) and few other databases. Currently, his research interest includes genome sequencing, transcriptomics and genome-wide association studies (GWAS) to improve the genetic and productive efficiency of livestock. He is also keen to develop fundamental knowledge and bioinformatics tools to facilitate genomic studies in animals.
1. Azam, S., Parthasarathy, S., Singh, C., Kumar, S. and Siddavattam, D., 2019. Genome organization and adaptive potential of archetypal organophosphate degrading Sphingobium fuliginis ATCC 27551. Genome biology and evolution, 11(9), pp.2557-2562.
2. Parthasarathy S, Azam S, Lakshman Sagar A, Narasimha Rao, et. al. 2017. Genome-guided insights reveal organophosphate-degrading Brevundimonas diminuta as Sphingopyxis wildii and define its versatile metabolic capabilities and environmental adaptations. Genome Biology and Evolution 9(1):77-81.
3. Faisal SM, Varma VP, Subathra M, Azam S, et. al. 2016. Leptospira surface adhesin (Lsa21) induces Toll like receptor 2 and 4 mediated inflammatory responses in macrophages. Scientific Reports 6:39530.
4. Azam S., Rao SB, Jakka P, Narasimha Rao V, Bhargavi B, Gupta VK, Radhakrishnan G. 2016. Genetic characterization and comparative genome analysis of Brucella melitensis isolates from India. International Journal of Genomics 2016:3034756.
5. Angela WH, Sharma M, Thatcher LF, Azam S, Hane JK., et al. 2016. Comparative genomics and prediction of conditionally dispensable sequences in legume–infecting Fusarium oxysporum formae speciales facilitates identification of candidate effectors. BMC Genomics 17:191.
6. Sinha P, Pazhamala LT, Singh VK, Saxena RK, Krishnamurthy L, Azam S., et al. 2015. Identification and validation of selected universal stress protein domain containing drought-responsive genes in pigeonpea (Cajanus cajan L.). Frontiers in Plant Science 6:1065.
7. Jaganathan D, Thudi M, Kale S, Azam S, et al. 2014. Genotyping-by-sequencing based intra-specific genetic map refines a ‘‘QTL-hotspot” region for drought tolerance in chickpea. Molecular Genetics and Genomics 290(2):559-71.
8. Kudapa H, Azam S, Sharpe AG, et al. 2014. Comprehensive transcriptome assembly of chickpea (Cicer arietinum) using Sanger and Next Generation Sequencing platforms: Development and applications. PLoS One 9(1):86039.
9. Azam S, Rathore A, Shah T, et al. 2013. ISMU: Integrated SNP mining and utilization pipeline for accelerated breeding. PLoS One 9(7):e101754.
10. Varshney RK, Song C, Saxena RK, Azam S, et al. 2013. Draft genome sequence of chickpea (Cicer arietinum) provides a resource for trait improvement. Nature Biotechnology 13(3):240-6.
11. Varshney RK, Chen W, Li Y, Bharti AK, Saxena RK, Schlueter, JA, Gonoghue MTA, Azam S, et al. 2012. Draft genome sequence of pigeonpea (Cajanus cajan), an orphan legume crop of resource-poor farmers. Nature Biotechnology 30:83–9.
Project Associate-I
Mr. Lokesh Kumar
Current Research Interest: Computational Biology, Bio-Informatics and Next Generation Sequencing (NGS) data analysis
1. Role of Investigator: Co-I
Title of the Project: Genomics for conservation of indigenous cattle breeds and for enhancing milk yield, Phase-I
Funding Agency: DBT
Period/Duration: 2017-2020
2. Role of Investigator: PI
Title of the Project: Identification of key molecular factors involved in resistance/susceptibility to paratuberculosis infection in indigenous breeds of cows
Funding Agency: DBT
Period/Duration: 2020-2023
Genomics and Computational Biology Laboratory, NIAB
National Institute of Animal Biotechnology
Survey No. 37, Opp. Journalist Colony
Extended Q City Road, Near Gowlidoddy
Gachibowli, Hyderabad
Telangana – 500032
Email: sarwar[at]niab[dot]org[dot]in
Tel: +91-(0)40-2312-0134
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