राष्ट्रीय पशु जैव प्रौद्योगिकी संस्थान

National Institute of Animal Biotechnology

An Autonomous Institute of the Department of Biotechnology,
Ministry of Science and Technology, Government of India


High Content Screening Facility


Operetta CLS™ high-content analysis system is an automated microscopy featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. With the simple, but powerful Harmony 4.5 software, Operetta CLS™ lets you find even subtle phenotypic changes and quantifies various cellular parameters – morphology, proliferation, apoptosis, protein expression, and intracellular localization and up to 50 multi-parametric datasets. Confocal spinning disk technology provides a fast and gentle imaging process, enabling efficient background rejection. Powerful, stable 8x LED light source for optimal excitation of your fluorophores and confidence in results and large format sCMOS camera delivers low noise, wide dynamic range, and high resolution – perfect for sensitive and quantitative measurements at short exposure times. Proprietary automated water-immersion objectives with very high numerical aperture enable high resolution and fast read times with minimal photo damage.

Applications ranging from 2D cell-based assays to 3D spheroid biology and multiplexable fluorescent reagents for screening of drug library, inhibitor library, protein-protein interaction, genome wide mutation assays etc.

Perkin Elmer: Operetta CLS-HH16000020

Working Condition: Working

Contact Person: 
Nilanjana Ganguli
Email: nilanjana[at]niab[dot]org[dot]in
Phone: +91 40 2312 0148

Scientist In-charge:
Dr Bappaditya Dey
Email: bdey[at]niab[dot]org[dot]in
Phone: +91 40 2312 0128

User Charges:
Central Univ. / Research institute/ Academia:

Start-up/ Incubatee: ₹1,800/hour
Established Industry: ₹2500/hour